定于 2013 年 8 月 17 日上午在上海召开“中华口腔医学会第 15 次全国口腔医学学术会议  

（2013 年会）”期间举办 “中华口腔医学会——登士柏口腔医学生研究论文英文壁报比赛”。  

今年比赛投稿采取各院校推荐或学生自愿发送电子邮件方式（投稿要求见后），参加预赛。  

经评审专家组网上投票后，推选出前 12 名优胜者参加决赛。  

12 名参加决赛者需赴上海参加在中华口腔医学会第 15 次全国口腔医学学术会议上举办的  

“中华口腔医学会—登士柏口腔医学生研究论文英文壁报比赛”决赛及颁奖仪式，届时不到者  

将视为自动放弃评奖资格。  

前 100 名优秀论文获得者可获得在第 15 次全国口腔医学学术会议上展出壁报的资格。  

决赛设一等奖 1 名、二等奖 3 名、三等奖 8 名。一等奖获得者将由登士柏公司支持参加一  

次国际口腔医学学术会议的经费。二等奖获得者将获得 1000 元奖学金，三等奖获得者将获得  

500 元奖学金。12 名决赛选手的注册费和住宿费由登士柏公司支持。  

参加比赛人员须为中国大陆口腔医学院校的七年制、八年制在校学生。  

投稿截止日期：2013 年 6 月 30 日  

提交论文摘要要求：  

1. 论文必须是以英文形式撰写的研究型论著。  

2. 文题：应简明确切反映本文的特定内容，一般不用副标题。尽可能不用代号。文题以  

不超过 9 词为宜。  

3. 作者单位、署名：作者单位名称应包含省、市、区、县名，在单位名称后用圆括弧写  

明邮政编码，空一格后接写作者姓名。不同单位的多作者稿应另起行写明第二或第三作者的单  

位名称、邮编、姓名。  

4. 研究型论著摘要文本分四段式书写，即目的、方法、结果、结论。  

5. 关键词：3-5 个关键词。  

6. 图表及参考文献等的处理：摘要中不用图、表、化学结构式及参考文献，应如实反映  

原文，不加评论。7. 名词使用：文中使用的名词应注意全稿前后统一，必须使用全国自然科学、社会科学  

名词委员会公布的各科名词，所用专用名词不要随意缩写，如所用名词过长，而文中又需多次  

使用，则应在第一次引用时在全名后加圆括号注明缩写。  

8. 计量单位：按我国的法定计量单位。标点符号、数字用法等均按国家标准执行。  

投稿手续：  

稿件请发至：firstgccd@gmail.com，并标明“登士柏口腔医学生研究论文英文壁报比赛”

投稿  

联系人：邓媛媛，联系方式；010-82195542  

中华口腔医学会  

2013 年 5 月  

2013年登士柏英文壁报比赛摘要提交的补充说明：

1、提交者必须是今年口腔长学制毕业生或在校生，研究内容可以是口腔临床或口腔基础研究。  

2、邮件的正文中需包含姓名，性别，手机号，院校全称，Email，英文标题。请在邮件正文中直接附上以下表格（填写时可以调整表格长度，但表格中尽量不要换行）：  

姓名	性别	手机号	院校全称	Email	英文标题

3、邮件的附件中需同时包含学生证扫描件和英文论文摘要，不要用压缩包形式发送。

4、学生证扫描件须包含姓名、院校、年级、注册和个人登记照这5项信息，如果不能在一张图片里显示这些信息，可以分成几张图片发送过来。提交的文件类型是jpg形式，文件名的提交格式是：学生证—院校简称+姓名，如：“学生证1—武大口腔王楠”。  

5、英文论文摘要的文件提交类型是word2003版。摘要中标题不要超过9个词，关键词不超过5个词，全文不超过300词，全文字号大小为“小四”，标题可加粗，摘要中不能加入图片和图表。个人和院校相关信息只能出现在标题下方第1至2行内，其他地方不允许出现。文件名的提交格式是：abstract—院校简称+姓名，如“abstract—武大口腔王楠”。 

6、每名参赛者只能提交一篇英文摘要，须为第一作者，不允许多名参赛者共用一篇摘要。  

7、提交的截止日期是2013年6月30日。  

8、稿件请发至：firstgccd@gmail.com，邮件主题中标明“登士柏口腔医学生研究论文英文壁报比赛投稿”。联系人：邓媛媛，手机：13718237892，QQ：7192389，请尽量用邮件或短信联系。

中华口腔医学会  

2013年5月  

 

现场比赛评分标准

 

JUDGE EVALUATION FORM

Number: _____________________

POSTER EVALUATION	SCORE GIVEN BY EVALUATOR
1. Poster meets guidelines (size, layout)
2. Title is explanatory, easy to identify sections
3. Tables, graphs, figures clearly labeled
4. Entire poster well laid out, neat/attractive
Total Points this Section is20
SCIENTIFIC RELEVANCE	SCORE GIVEN BY EVALUATOR
5. Background sufficient
6. Logical sequence
7.Scientifically sound & supported
8. Creative ability, new approach
Total Points this Section is20
EXPERIMENTAL DESIGN	SCORE GIVEN BY EVALUATOR
9. Objectives well stated
10. Experiments described clearly
11. Experimental design appropriate
12. Statistical method applied correctly
Total Points this Section is20
RESULTS & CONCLUSIONS	SCORE GIVEN BY EVALUATOR
13. Results significant, original, sound
14. Appropriate controls
15. Conclusions appropriate to results
Total Points this Section is15
PRESENTATION	SCORE GIVEN BY EVALUATOR
16. Student understands research
17. Professional appearance
18. Presented logically,within the time limit
19. Answered questions effectively
20. Speak English fluently
Total Points this Section is25

Comments:  

Signature of Judge: TOTAL POINTS:  

Maximum = 100 Points  

Abstract 1  

Activity of Antimicrobial Peptide Mimetics Against Candida  

R. Yamarthy and G. Diamond  

Objectives: Oral candidiasis, an infection mainly caused by the fungus Candida albicans, is an increasing problem in AIDS and other immuno-compromising diseases. In the last few years, antimicrobial peptides have shown promise as effective antifungal treatments. As these peptides are expensive to produce, Polymedix, Inc., has developed a set of inexpensive compounds that mimic the structure of antimicrobial peptides. The goal of this investigation is to examine the activity of antimicrobial peptide mimetics to develop novel therapies against Candidal infections.  

Methods: Two different peptide mimetics were tested, PMX 30016 and mPE. These compounds were tested to determine kinetics of killing, minimal fungicidal concentration (MFC), viability of candida in a denture biofilm using an XTT assay, and synergy with chlorohexidine and Itraconazole.  

Results: The MFCs of mPE and PMX 30016 against C. albicans were determined to be 2 μg/mL and 0.25 μg/mL, respectively. Other Candidal species had MFC’s ranging from 0.25 to 1 μg/mL. There was potent synergy between both compounds and Itraconazole. Kinetics of killing experiments showed that C. albicans blastoconidia were eliminated completely within 20 minutes at an mPE dose equivalent to five times the MIC. XTT studies showed that the metabolic activity of C. albicans decreased as the concentration of PMX 30016 increased.  

Conclusion: Peptide-mimetics can form the basis for the development of novel therapies against candidal infections.  

Abstract 2  

Comparing suture strengths for clinical applications - A novel In-vitro study  

Background: To achieve a good healing of the surgical site, flaps should be approximated and held in place by sutures. Strength and durability of sutures are critical to successful healing. The most commonly used absorbable sutures in dentistry are chromic gut and polyglactin (PGN). A newer form of fast absorbing polyglactin (PGN FA) has been introduced in the market with claims of similar strength and faster absorption compared to regular PGN. The goal of this study was to assess tensile strength of these three suture materials kept in a simulated oral environment over time to determine which is best for clinical applications.  

Methods: A total of 252 samples consisting of two different gauges of each suture material made up the sample size. Each sample was tied and pre-tensioned to 10.2  

Newtons and placed in a simulated oral environment. Samples were tested at specified  

time points ranging up to 14 days. A micro-tensile strength tester was used with a linear  

load of 0.04mm/sec. Results were recorded and tabulated for statistical analysis. Light  

microscopy was used to analyze the nature of failure whether shredded or straight  

severance.  

Results and Conclusions: PGN showed the greatest initial tensile strength yet steadily  

lost strength. Chromic gut showed the greatest stability of strength over the two weeks.  

PGN FA was the weakest of all materials tested and was completely absorbed in 10 days.  

PGN FA is not a good material for dental surgical applications requiring a longer healing  

time.  

Abstract 3  

Comparison of the Effect of Hemostatic Agents on Collagen Induced  

Platelet Aggregation  

Akindeko D. Obebe, Class of 2009, Kornberg School of Dentistry, Temple University  

Objectives: Hemostasis subsequent to tooth extraction consists of contraction of blood  

vessels, platelet aggegation and plug formation, coagulation and clot formation. The  

purpose of this research is to compare the effect of various commercial hemostatic agent  

on the platelet aggregation phase of hemostasis.  

Methods: The following commercial hemostatic agents were ground into small fibers  

and suspended at a concentration of 1 mg/ml: Collaplug, Bloodstop, Surgicel, Gelfoam,  

Surgifoam, Quick-clot. Hemcon dental dressing was solubilized at 1mg/ml. Platelet rich  

plasma (PRP) was prepared from anticoagualted whole blood. For platelet aggregation  

assays, PRP (108 platelets/ml, 450μl) were activated with either collagen (1 mg/ml 10 μl),  

or collagen mixed with hemostatic agent (each at 1 mg/ml). The effect of each agent on  

collagen induce platelet aggregation was measured on a platelet aggregometer.  

Results: Collaplug, Hemcon and Quick-clot enhance collagen induced aggregation by  

50%, 20%, and 12 % respectively. Bloodstop, Surgicel, Gelfoam did not effect collagen  

induced platelet aggregation.  

Conclusion: Although all of the commercial products are known to be effective aids in  

achieving hemostasis, only Collaplug , Hemcon, and Quick-clot enhance the platelet  

aggregation phase of hemostasis.  

Abstract 4  

Effect of Adhesive System and Composite Type on Dentin Bonds  

Todd Walker, Neil Jessop, Gerard Kugel, Paul Stark.  

Objective:  

To evaluate the effect of different adhesive systems and composites combinations on  

dentinal bond strength.  

Methods:  

The bond strength of 7 self-etching and 5 total-etching adhesive systems (Peak LC/Peak  

SE, Peak LC/Ultra Etch, Clear Fil SE Bond, Clear Fil S3, OptiBond AIO, Xeno IV,  

Prompt, All Bond 3, PQ1/Ultra Etch, Opti Bond Solo, P&B NT, Single Bond, One Step)  

and 8 composite material combinations (Z100, FilTech Supreme, Vit-L-Escence,  

Amelogen Plus, Premise, Opalis, Esthet X, Flow IT) were tested by measuring the MPa  

of adhesive to dentin using an Instron shear test. Extracted human molars were prepared,  

sectioned w/ a diamond blade, and exposed dentin was polished with 600-grit abrasive  

paper. Samples were randomly chosen and prepared following instructions from each  

company’s adhesive system and composite application onto a 2.39 mm diameter button.  

Specimens were incubated in 37 degrees C water for 24 hours before MPa testing. Seven  

replicates were analyzed for each combination. Generalized linear models were utilized  

to test these comparisons. By performing these global tests, the impact of multiple  

comparisons is negated.  

Results:  

Results of bond strength were found to be highly statistically significant in relation to  

both composite type and adhesive systems (pAmelogen Plus and Z100 composites resulted in the highest bonding strength. The  

adhesive Peak LC demonstrated the highest bonding strength of all adhesives tested. The  

highest values found used the combination of Amelogen Plus and Peak LC. Total Etch  

systems were, on average, 4.2 MPa higher than other etching products (p=0.003)  

Conclusion:  

These results suggest that, while both factors significantly affect bonding strength, the  

adhesive is the most important determinant. This is due to the magnitude of the range  

between the highest and lowest adhesive compared to the highest and lowest composite.  

Abstract 5  

BMP Signaling is Required for Development of the Maxillary Process  

B. WANG, S. FOPPIANO, D. HU, and R. S. MARCUCIO  

Objectives: To assess morphological effects of blocking BMP signaling at different time  

points within the ectoderm or mesenchyme of the avian maxillary process.  

Methods: A replication competent retrovirus encoding Noggin (RCAS-Noggin) (control  

RCAS-Alkaline Phosphatase (RCAS-AP)) was injected into the mesenchyme or onto  

surface ectoderm of the right maxillary process of chick embryos at Hamburger-Hamilton stage 20 (HH20) or HH24. Embryos infected at HH20 were harvested at HH24, HH28, HH32, and HH39. Embryos infected at HH24 were harvested at HH32, and HH39.  

Results: Infection of the ectoderm with RCAS-Noggin at HH20 (n=12/13) resulted in no aberrant phenotype. Similarly, control embryos infected with RCAS-AP appeared normal (HH20 n=28/28). Infection with RCAS-Noggin in the mesenchyme at HH20, resulted in severe malformations at HH39 (n=3/3). Control embryos showed normal phenotype (n=1).To elucidate the mechanism(s) underlying the aberrant phenotype, embryos were examined at earlier time points. Facial primordia appeared unaffected at HH24 (n=7/7), and showed a minor phenotype at HH28 (n=3/4). Infection of the mesenchyme at HH24 resulted in a similar, but less severe phenotype at ~HH39.  

Conclusions: Blockade of BMP signaling in the ectoderm does not result in abnormal phenotype. Infection of the mesenchyme of the maxillary process with RCAS-Noggin results in severe facial dysmorphologies.  

These malformations likely occur primarily as a result of disrupted skeletogenesis. Timing of BMPs signaling blockade affects the severity of phenotype.  

Support: T32 DE07306-12, 1R01DE018234-01  

Abstract 6  

Characterization of a Novel Assay for Orofacial Hyperalgesia and Allodynia  

Susan Putthoff, Jill Fehrenbacher PhD, Michael Henry DDS, PhD, Kenneth Hargreaves DDS, PhD  

Objectives: The aim of this study was to characterize behavioral responses to mechanical and thermal stimuli to the vibrissal pad region of rats using a new model to evaluate orofacial nociception. Methods: Animals were trained in 20 min intervals to voluntarily place their face against either thermal or mechanical stimuli to provide access to a reward, a bottle with condensed milk solution. Copper tubing shaped to contact the vibrissal pad region and warmed by heated water circulating through it was used to deliver the thermal test stimulus; animals were tested over a temperature range of 40-63ºC. The mechanical stimuli was provided by an insert with 0-32 nickel titanium wires attached to a plastic ring which made contact with the vibrissal pad region when the animal accessed the reward. Experimental testing sessions were 10 minutes and endpoints that were measured were the duration of feeding, measured by accumulated breakage of an infrared beam which crosses the opening to the reward, and number of feeding attempts, measured by the number of times the infrared beam was broken. Results: A significant decrease in feeding time and increase in number of feeding attempts was observed with increasing temperature. Similar to the thermal stimulus response a decrease in feeding time was also detected with increasing mechanical force induced by increased numbers of nickel titanium wires, although the number of beam breaks did not correspond to an increase in force. Conclusions: A  

decrease in feeding time was evaluated as an increase in nociception. Feeding duration was seen to decrease with increasing thermal and mechanical stimuli. This behavioral model will be a useful index of animal nociception and possible therapeutics in the orofacial region. This work was supported by NIDCR grant DE14318 for CO STAR.  

Abstract 7  

Effects of Gender and Periapical Inflammation on Rat Adipose Tissue  

Ritter SA*, Sandifer LC, Bain JL, Caskey CP, Balius KE, Naftel JP, Johnson RB  

Objective: The objective of this study was to compare the serum and omentum concentrations of leptin and interleukin (IL)-6 between female and male rats with periapical tooth abscesses.  

Methods: 48 Sprague-Dawley rats were studied. They were divided into two groups: those with experimentally-induced periapical abscesses and sham-operated controls. To create the abscesses, the pulps of the first and second maxillary molar teeth were exposed using a ¼ round bur. 24 days later, serum, and the greater omentum were collected and immediately frozen. The tissue samples were ground in PBS containing a protease inhibitor (10 mg tissue/ml PBS/protease inhibitor). The total protein content of the serum and tissue samples was determined using a bicinchoinic acid protein assay; the tissue and serum concentrations of IL-6 and leptin were determined by ELISA. Data were expressed as pg IL-6 or leptin/mg protein. The outcome variables were compared by factorial analysis of variance and a post-hoc Tukey test.  

Results: Males with periapical abscesses had significantly greater serum IL-6 and greater omentum concentrations (pConclusion: Male rats with periapical abscesses had a greater acute phase response to periapical inflammation than females and greater accumulation of IL-6 within the greater omentum. Thus, males with tooth abscesses may be at greater risk for obesity-related and cardiovascular diseases than females with abscessed teeth.  

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